Human MECR protein (Recombinant) (N-His) (STJP008008)

SKU:
STJP008008
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MECR-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MECR
Gene ID: 51102
Uniprot ID: MECR_HUMAN
Immunogen Region: Arg42-Met373
Immunogen: Homo sapiens (Human)
Function Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. Involved in iron homeostasis.affecting Fe-S cluster assembly and ceramide metabolism. Required for proper morphology and bioenergetic functions of mitochondria. Required for maintenance of neurons.
Protein Name Enoyl-Acyl-Carrier-Protein Reductase - Mitochondrial
2-Enoyl Thioester Reductase
Nuclear Receptor-Binding Factor 1
Hsnrbf-1
Nrbf-1
Database Links Reactome: R-HSA-77346
Cellular Localisation Isoform 1: Mitochondrion
Isoform 2: Cytoplasm
Nucleus
Alternative Protein Names Enoyl-Acyl-Carrier-Protein Reductase - Mitochondrial protein
2-Enoyl Thioester Reductase protein
Nuclear Receptor-Binding Factor 1 protein
Hsnrbf-1 protein
Nrbf-1 protein
MECR protein
NBRF1 protein
CGI-63 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells
STJP003488 Human CFD protein (Recombinant) (N-His) (STJP003488) E. coli

Related Products

!