Human MDH1 protein (Recombinant) (N-GST) (STJP004685)

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STJP004685
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MDH1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MDH1
Gene ID: 4190
Uniprot ID: MDHC_HUMAN
Immunogen Region: Ser2-Ala334
Immunogen: Homo sapiens (Human)
Function Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS).
Protein Name Malate Dehydrogenase - Cytoplasmic
Aromatic Alpha-Keto Acid Reductase
Kar
Cytosolic Malate Dehydrogenase
Database Links Reactome: R-HSA-9856872
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Malate Dehydrogenase - Cytoplasmic protein
Aromatic Alpha-Keto Acid Reductase protein
Kar protein
Cytosolic Malate Dehydrogenase protein
MDH1 protein
MDHA protein

Information sourced from Uniprot.org