Human MBOAT4/GOAT protein (Recombinant) (N-His) (STJP008762)

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STJP008762
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MBOAT4/GOAT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MBOAT4
Gene ID: 619373
Uniprot ID: MBOA4_HUMAN
Immunogen Region: Phe64-Ala162
Immunogen: Homo sapiens (Human)
Post Translational Modifications Not glycosylated.
Function Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity. In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient.
Protein Name Ghrelin O-Acyltransferase
Membrane-Bound O-Acyltransferase Domain-Containing Protein 4
O-Acyltransferase Domain-Containing Protein 4
Database Links Reactome: R-HSA-422085
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Ghrelin O-Acyltransferase protein
Membrane-Bound O-Acyltransferase Domain-Containing Protein 4 protein
O-Acyltransferase Domain-Containing Protein 4 protein
MBOAT4 protein
GOAT protein
OACT4 protein
FKSG89 protein

Information sourced from Uniprot.org