Human MAX protein (Recombinant) (N-His-SUMO) (STJP014560)

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STJP014560-100
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Short Description :Recombinant-Human MAX-N-His-SUMO protein was developed from e.coli and has a target region of N-His-SUMO. For use in research applications.
Applications:ELISA/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for this information.
Gene Symbol:MAX
Gene ID:4149
Uniprot ID:MAX_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala22-Ser107
Post Translational Modifications Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name Protein Max
Class D Basic Helix-Loop-Helix Protein 4
Bhlhd4
Myc-Associated Factor X
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-69202
Reactome: R-HSA-69656
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Cell Projection
Dendrite
Alternative Protein Names Protein Max protein
Class D Basic Helix-Loop-Helix Protein 4 protein
Bhlhd4 protein
Myc-Associated Factor X protein
MAX protein
BHLHD4 protein

Information sourced from Uniprot.org

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