| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human MAP3K13-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | MAP3K13 |
| Gene ID: | 9175 |
| Uniprot ID: | M3K13_HUMAN |
| Immunogen Region: | Trp161-Pro418 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Autophosphorylated on serine and threonine residues. |
| Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 13Leucine Zipper-Bearing KinaseMixed Lineage KinaseMlk |
| Database Links | |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Protein Names | Mitogen-Activated Protein Kinase Kinase Kinase 13 proteinLeucine Zipper-Bearing Kinase proteinMixed Lineage Kinase proteinMlk proteinMAP3K13 proteinLZK protein |
Information sourced from Uniprot.org