| Post Translational Modifications | Autophosphorylated on serine and threonine residues. |
| Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 13Leucine Zipper-Bearing KinaseMixed Lineage KinaseMlk |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Protein Names | Mitogen-Activated Protein Kinase Kinase Kinase 13 proteinLeucine Zipper-Bearing Kinase proteinMixed Lineage Kinase proteinMlk proteinMAP3K13 proteinLZK protein |
Information sourced from Uniprot.org
