Human MAFG protein (Recombinant) (N-His) (STJP003251)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MAFG-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MAFG |
| Gene ID | 4097 |
| Uniprot ID | MAFG_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ser162 |
Additional Info
| Post Translational Modifications | Acetylated in erythroid cells by CREB-binding protein (CBP). Acetylation augments the DNA-binding activity of NFE2, but has no effect on binding NFE2. Sumoylation at Lys-14 is required for active transcriptional repression. |
| Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NFE2L2. Activates globin gene expression when associated with NFE2L2. May be involved in signal transduction of extracellular H(+). |
| Protein Name | Transcription Factor MafgV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog GHmaf |
| Database Links | Reactome: R-HSA-9759194Reactome: R-HSA-9818028Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Transcription Factor Mafg proteinV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G proteinHmaf proteinMAFG protein |
Information sourced from Uniprot.org