| Short Description : | Recombinant-Human MafF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAFF |
| Gene ID: | 23764 |
| Uniprot ID: | MAFF_HUMAN |
| Accession Number: | NP_001155045 |
| Immunogen: | Human |
| Immunogen Region: | 1-164aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSVDPLS SKALKIKREL SENTPHLSDE ALMGLSVREL NRHLRGLSAE EVTRLKQRRR TLKNRGYAAS CRVKRVCQKE ELQKQKSELE REVDKLAREN AAMRLELDAL RGKCEALQGF ARSVAAARGP ATLVAPASVI TIVKSTPGSG SGPAHGPDPA HGPASCS |
| Tissue Specificity | Expressed in the term myometrium and kidney. |
| Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. |
| Protein Name | Transcription Factor MaffU-MafV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Transcription Factor Maff proteinU-Maf proteinV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F proteinMAFF protein |
Information sourced from Uniprot.org