| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human LYPD3 Protein at 1 Mu g/mL (100 Mu L/well) can bind LYPD3 Rabbit pAb with a linear range of 0.06-3.84 ng/mL. |
| Gene Symbol: |
LYPD3 |
| Gene ID: |
27076 |
| Uniprot ID: |
LYPD3_HUMAN |
| Immunogen Region: |
Leu31-His286 |
| Immunogen: |
Recombinant Human LYPD3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu31-His286) of human LYPD3/C4.4A (Accession #NP_055215.2.) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
LECYSCVQKADDGCSPNKMK TVKCAPGVDVCTEAVGAVET IHGQFSLAVRGCGSGLPGKN DRGLDLHGLLAFIQLQQCAQ DRCNAKLNLTSRALDPAGNE SAYPPNGVECYSCVGLSREA CQGTSPPVVSCYNASDHVYK GCFDGNVTLTAANVTVSLPV RGCVQDEFCTRDGVTGPGFT LSGSCCQGSRCNSDLRNKTY FSPRIPPLVRLPPPEPTTVA STTSVTTSTSAPVRPTSTT |
| Tissue Specificity | Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. |
| Post Translational Modifications | N-glycosylated and O-glycosylated. |
| Function | Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression. |
| Protein Name | Ly6/Plaur Domain-Containing Protein 3Gpi-Anchored Metastasis-Associated Protein C4.4a HomologMatrigel-Induced Gene C4 ProteinMig-C4 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Ly6/Plaur Domain-Containing Protein 3 proteinGpi-Anchored Metastasis-Associated Protein C4.4a Homolog proteinMatrigel-Induced Gene C4 Protein proteinMig-C4 proteinLYPD3 proteinC4.4A proteinUNQ491 proteinPRO1007 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
