| Short Description : | Recombinant-Human LSM2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 40% Glycerol, 200mM NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LSM2 |
| Gene ID: | 57819 |
| Uniprot ID: | LSM2_HUMAN |
| Accession Number: | NP_067000 |
| Immunogen: | Human |
| Immunogen Region: | 1-95aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMLFYSF FKSLVGKDVV VELKNDLSIC GTLHSVDQYL NIKLTDISVT DPEKYPHMLS VKNCFIRGSV VRYVQLPADE VDTQLLQDAA RKEALQQKQ |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. |
| Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm2Protein G7bSmall Nuclear Ribonuclear Protein D HomologSnrnp Core Sm-Like Protein Sm-X5 |
| Database Links | Reactome: R-HSA-430039Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | U6 Snrna-Associated Sm-Like Protein Lsm2 proteinProtein G7b proteinSmall Nuclear Ribonuclear Protein D Homolog proteinSnrnp Core Sm-Like Protein Sm-X5 proteinLSM2 proteinC6orf28 proteinG7B protein |
Information sourced from Uniprot.org
