Human LRRFIP1 protein (Recombinant) (N-His) (STJP005531)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LRRFIP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LRRFIP1 |
| Gene ID | 9208 |
| Uniprot ID | LRRF1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp615-Ser735 |
Additional Info
| Function | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
| Protein Name | Leucine-Rich Repeat Flightless-Interacting Protein 1Lrr Flii-Interacting Protein 1Gc-Binding Factor 2Tar Rna-Interacting Protein |
| Database Links | Reactome: R-HSA-1839117Reactome: R-HSA-3134973Reactome: R-HSA-5655302 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Protein Names | Leucine-Rich Repeat Flightless-Interacting Protein 1 proteinLrr Flii-Interacting Protein 1 proteinGc-Binding Factor 2 proteinTar Rna-Interacting Protein proteinLRRFIP1 proteinGCF2 proteinTRIP protein |
Information sourced from Uniprot.org