Name: Human LRRC4 protein (Recombinant) (C-His) (STJP001209)
SKU: STJP001209
Availability: InStock

Human LRRC4 protein (Recombinant) (C-His) (STJP001209)

SKU:

STJP001209

£106.50 - £232.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 1.0 EU/Mu g of the protein by LAL method.

Gene Symbol:	LRRC4
Gene ID:	64101
Uniprot ID:	LRRC4_HUMAN
Immunogen Region:	Ala39-Lys527
Immunogen:	Recombinant Human LRRC4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala39-Lys527) of human LRRC4 (Accession #NP_071426.1.) fused with a 6×His tag at the C-terminus.
Immunogen Sequence:	ASAGPQNCPSVCSCSNQFSK VVCTRRGLSEVPQGIPSNTR YLNLMENNIQMIQADTFRHL HHLEVLQLGRNSIRQIEVGA FNGLASLNTLELFDNWLTVI PSGAFEYLSKLRELWLRNNP IESIPSYAFNRVPSLMRLDL GELKKLEYISEGAFEGLFNL KYLNLGMCNIKDMPNLTPLV GLEELEMSGNHFPEIRPGSF HGLSSLKKLWVMNSQVSLIE RNAFDGLASLVELNLAHNN

Tissue Specificity	Specifically expressed in brain.
Post Translational Modifications	N-glycosylated.
Function	Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma.
Protein Name	Leucine-Rich Repeat-Containing Protein 4 Brain Tumor-Associated Protein Bag Nasopharyngeal Carcinoma-Associated Gene 14 Protein Netrin-G2 Ligand Ngl-2
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein Postsynaptic Cell Membrane Lrrc4 And Dlg4 Are Interdependent For Synaptic Localization
Alternative Protein Names	Leucine-Rich Repeat-Containing Protein 4 protein Brain Tumor-Associated Protein Bag protein Nasopharyngeal Carcinoma-Associated Gene 14 Protein protein Netrin-G2 Ligand protein Ngl-2 protein LRRC4 protein BAG protein NAG14 protein UNQ554 protein PRO1111 protein

Information sourced from Uniprot.org

Human LRRC4 protein (Recombinant) (C-His) (STJP001209)