| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human LRIG1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | LRIG1 |
| Gene ID: | 26018 |
| Uniprot ID: | LRIG1_HUMAN |
| Immunogen Region: | Cys45-Val397 |
| Immunogen: | Homo sapiens (Human) |
| Function | Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. |
| Protein Name | Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1Lig-1 |
| Database Links | Reactome: R-HSA-177929Reactome: R-HSA-6807004Reactome: R-HSA-9725554 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1 proteinLig-1 proteinLRIG1 proteinLIG1 protein |
Information sourced from Uniprot.org
