| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 1.15ng/mL |
| Detection Limit: | 3.12-200ng/mL |
| Short Description : | This LPCAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | LPCAT1 |
| Gene ID: | 79888 |
| Uniprot ID: | PCAT1_HUMAN |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Erythrocytes. |
| Post Translational Modifications | |
| Function | Exhibits acyltransferase activity. Exhibits acetyltransferase activity. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 1 Lpc Acyltransferase 1 Lpcat-1 Lysopc Acyltransferase 1 1-Acylglycerol-3-Phosphate O-Acyltransferase 1-Acylglycerophosphocholine O-Acyltransferase 1-Alkenylglycerophosphocholine O-Acyltransferase 1-Alkylglycerophosphocholine O-Acetyltransferase Acetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase Acetyl-Coa -Lyso-Paf Acetyltransferase Lyso-Paf Acetyltransferase Lysopafat Acyltransferase-Like 2 Phosphonoformate Immuno-Associated Protein 3 |
| Database Links | Reactome: R-HSA-1482788 Reactome: R-HSA-1482925 Reactome: R-HSA-1483166 Reactome: R-HSA-1483191 Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Type Ii Membrane Protein Golgi Apparatus Membrane Cell Membrane Lipid Droplet May Adopt A Monotopic Topology When Embedded In The Lipid Monolayer Of The Lipid Droplet With Both Termini Exposed To The Cytoplasm |
| Alternative ELISA Names | Lysophosphatidylcholine Acyltransferase 1 ELISA kit Lpc Acyltransferase 1 ELISA kit Lpcat-1 ELISA kit Lysopc Acyltransferase 1 ELISA kit 1-Acylglycerol-3-Phosphate O-Acyltransferase ELISA kit 1-Acylglycerophosphocholine O-Acyltransferase ELISA kit 1-Alkenylglycerophosphocholine O-Acyltransferase ELISA kit 1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kit Acetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase ELISA kit Acetyl-Coa -Lyso-Paf Acetyltransferase ELISA kit Lyso-Paf Acetyltransferase ELISA kit Lysopafat ELISA kit Acyltransferase-Like 2 ELISA kit Phosphonoformate Immuno-Associated Protein 3 ELISA kit LPCAT1 ELISA kit AYTL2 ELISA kit PFAAP3 ELISA kit |
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Information sourced from Uniprot.org