Human LMW-PTP/ACP1 protein (Recombinant) (His-Tag) (STJP016429)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human LMW-PTP/ACP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM MES buffer (pH 6.0) containing 0.1mM PMSF, 2mM EDTA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 15, 000unit/mg, and is defined as the amount of enzyme that hydrolyze 1.0nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C. |
Target Information
| Gene Symbol | ACP1 |
| Gene ID | 52 |
| Uniprot ID | PPAC_HUMAN |
| Accession Number | NP_009030.1 |
| Immunogen | Human |
| Immunogen Region | 1-158aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform 2: Expressed in T-lymphocytes. |
| Post Translational Modifications | Isoform 2: Phosphorylated by LCK. Phosphorylation at Tyr-132 increases its phosphatase activity. Isoform 3: Not phosphorylated. |
| Function | Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2. Isoform 3: Does not possess phosphatase activity. |
| Protein Name | Low Molecular Weight Phosphotyrosine Protein PhosphataseLmw-PtpLmw-PtpaseAdipocyte Acid PhosphataseLow Molecular Weight Cytosolic Acid PhosphataseRed Cell Acid Phosphatase 1 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Low Molecular Weight Phosphotyrosine Protein Phosphatase proteinLmw-Ptp proteinLmw-Ptpase proteinAdipocyte Acid Phosphatase proteinLow Molecular Weight Cytosolic Acid Phosphatase proteinRed Cell Acid Phosphatase 1 proteinACP1 protein |
Information sourced from Uniprot.org