Tissue Specificity | |
Post Translational Modifications | |
Function | Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. |
Protein Name | Serine/Threonine-Protein Kinase Lmtk3Lemur Tyrosine Kinase 3 |
Database Links | |
Cellular Localisation | MembraneSingle-Pass Membrane ProteinCell ProjectionAxonDendriteGolgi Apparatus MembranePunctate Pattern In Cell Projections |
Alternative ELISA Names | Serine/Threonine-Protein Kinase Lmtk3 ELISA kitLemur Tyrosine Kinase 3 ELISA kitLMTK3 ELISA kitKIAA1883 ELISA kitTYKLM3 ELISA kit |
output | |
Information sourced from Uniprot.org