Function | Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration. |
Protein Name | Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1Particularly Interesting New Cys-His Protein 1Pinch-1Renal Carcinoma Antigen Ny-Ren-48 |
Database Links | Reactome: R-HSA-446353Reactome: R-HSA-446388 |
Cellular Localisation | Cell JunctionFocal AdhesionCell MembranePeripheral Membrane ProteinCytoplasmic Side |
Alternative Protein Names | Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1 proteinParticularly Interesting New Cys-His Protein 1 proteinPinch-1 proteinRenal Carcinoma Antigen Ny-Ren-48 proteinLIMS1 proteinPINCH proteinPINCH1 protein |
Information sourced from Uniprot.org