Human LGI3 protein (Recombinant) (N-His) (STJP005686)

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STJP005686
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LGI3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LGI3
Gene ID: 203190
Uniprot ID: LGI3_HUMAN
Immunogen Region: Lys261-Ala548
Immunogen: Homo sapiens (Human)
Function May participate in the regulation of neuronal exocytosis.
Protein Name Leucine-Rich Repeat Lgi Family Member 3
Lgi1-Like Protein 4
Leucine-Rich Glioma-Inactivated Protein 3
Database Links Reactome: R-HSA-5682910
Cellular Localisation Secreted
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle
Synapse
Synaptosome
Cell Projection
Axon
Found In The Synaptosomal Membrane Fraction
Within Peripheral Myelinated Axons
Lgi3 Is Highly Expressed At The Juxtaparanodal Membrane And Colocalizes With The Voltage-Gated Potassium Channels Kv1
1 (Kcna1) And Kv1
2 (Kcna2)
And With Cntnap2
Dlg4
Adam22 And Adam23
Alternative Protein Names Leucine-Rich Repeat Lgi Family Member 3 protein
Lgi1-Like Protein 4 protein
Leucine-Rich Glioma-Inactivated Protein 3 protein
LGI3 protein
LGIL4 protein
UNQ8190 protein
PRO23199 protein

Information sourced from Uniprot.org