| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human LDLRAD3-N-Fc protein was developed from mammalian cells and has a target region of N-Fc. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | LDLRAD3 |
| Gene ID: | 143458 |
| Uniprot ID: | LRAD3_HUMAN |
| Immunogen Region: | Gln18-Thr173 |
| Immunogen: | Homo sapiens (Human) |
| Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation. (Microbial infection) Acts as a receptor for Venezuelan equine encephalitis virus. |
| Protein Name | Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3Ldlr Class A Domain-Containing Protein 3 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3 proteinLdlr Class A Domain-Containing Protein 3 proteinLDLRAD3 proteinLRAD3 protein |
Information sourced from Uniprot.org