| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human LAMA5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | LAMA5 |
| Gene ID: | 3911 |
| Uniprot ID: | LAMA5_HUMAN |
| Immunogen Region: | Pro2736-Cys2929 |
| Immunogen: | Homo sapiens (Human) |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2. |
| Protein Name | Laminin Subunit Alpha-5Laminin-10 Subunit AlphaLaminin-11 Subunit AlphaLaminin-15 Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Protein Names | Laminin Subunit Alpha-5 proteinLaminin-10 Subunit Alpha proteinLaminin-11 Subunit Alpha proteinLaminin-15 Subunit Alpha proteinLAMA5 proteinKIAA0533 proteinKIAA1907 protein |
Information sourced from Uniprot.org