Human LAMA3 protein (Recombinant) (N-His) (STJP005518)

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STJP005518
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LAMA3-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LAMA3
Gene ID: 3909
Uniprot ID: LAMA3_HUMAN
Immunogen Region: Leu47-Gly296
Immunogen: Homo sapiens (Human)
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Protein Name Laminin Subunit Alpha-3
Epiligrin 170 Kda Subunit
E170
Epiligrin Subunit Alpha
Kalinin Subunit Alpha
Laminin-5 Subunit Alpha
Laminin-6 Subunit Alpha
Laminin-7 Subunit Alpha
Nicein Subunit Alpha
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-2022090
Reactome: R-HSA-2214320
Reactome: R-HSA-3000157
Reactome: R-HSA-3000171
Reactome: R-HSA-3000178
Reactome: R-HSA-446107
Reactome: R-HSA-8874081
Reactome: R-HSA-9913351
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Basement Membrane
Major Component
Alternative Protein Names Laminin Subunit Alpha-3 protein
Epiligrin 170 Kda Subunit protein
E170 protein
Epiligrin Subunit Alpha protein
Kalinin Subunit Alpha protein
Laminin-5 Subunit Alpha protein
Laminin-6 Subunit Alpha protein
Laminin-7 Subunit Alpha protein
Nicein Subunit Alpha protein
LAMA3 protein
LAMNA protein

Information sourced from Uniprot.org