Human KRT8 (Keratin 8) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016623)

Name: Human KRT8 (Keratin 8) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016623)
SKU: STJE0016623
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SPECIFICATIONS

STJE0016623

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Short Description	This KRT8 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids..
Applications	ELISA
Reactivity	Human
Sensitivity	0.057ng/mL
Detection Limit	0.156-10ng/mL
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Storage Instruction	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time	3 hrs

Gene Symbol	KRT8
Gene ID	3856
Uniprot ID	K2C8_HUMAN
Immunogen Region	Ready-To-Use
Sample Type	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
Post Translational Modifications	Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization. O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation. O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
Function	Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Protein Name	Keratin - Type Ii Cytoskeletal 8 Cytokeratin-8 Ck-8 Keratin-8 K8 Type-Ii Keratin Kb8
Database Links	Reactome: R-HSA-6805567 Reactome: R-HSA-6809371
Cellular Localisation	Cytoplasm Nucleus Nucleoplasm Nucleus Matrix
Alternative ELISA Names	Keratin - Type Ii Cytoskeletal 8 ELISA kit Cytokeratin-8 ELISA kit Ck-8 ELISA kit Keratin-8 ELISA kit K8 ELISA kit Type-Ii Keratin Kb8 ELISA kit KRT8 ELISA kit CYK8 ELISA kit
output

Information sourced from Uniprot.org