SDS-PAGE gel of recombinant human KRT5 protein 3μg under reducing conditions with Coomassie blue stain

Human KRT5 protein (Recombinant) (His-Tag) (STJP018737)

SKU:
STJP018737
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human KRT5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:KRT5
Gene ID:3852
Uniprot ID:K2C5_HUMAN
Accession Number:AAH24292
Immunogen:Human
Immunogen Region:1-590aa
Immunogen Sequence:MSRQSSV SFRSGGSRSF STASAITPSV SRTSFTSVSR SGGGGGGGFG RVSLAGACGV GGYGSRSLYN LGGSKRISIS TSGGSFRNRF GAGAGGGYGF GGGAGSGFGF GGGAGGGFGL GGGAGFGGGF GGPGFPVCPP GGIQEVTVNQ SLLTPLNLQI DPSIQRVRTE EREQIKTLNN KFASFIDKVR FLEQQNKVLD TKWTLL
Tissue Specificity Expressed in corneal epithelium (at protein level). Expressed in keratinocytes (at protein level).
Post Translational Modifications Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle. Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis. CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury. O-glycosylated.
Function Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress. Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes.
Protein Name Keratin - Type Ii Cytoskeletal 5
58 Kda Cytokeratin
Cytokeratin-5
Ck-5
Keratin-5
K5
Type-Ii Keratin Kb5
Database Links Reactome: R-HSA-446107
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Reactome: R-HSA-9725554
Cellular Localisation Cytoplasm
Alternative Protein Names Keratin - Type Ii Cytoskeletal 5 protein
58 Kda Cytokeratin protein
Cytokeratin-5 protein
Ck-5 protein
Keratin-5 protein
K5 protein
Type-Ii Keratin Kb5 protein
KRT5 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP004072 Human KRT5 protein (Recombinant) (N-His) (STJP004072) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP019690 Human IRF2 protein (Recombinant) (His-Tag) (STJP019690) E.coli SDS-PAGE
STJP017768 Human CSTF1 protein (Recombinant) (His-Tag) (STJP017768) E.coli SDS-PAGE/Denatured
STJP017869 Human RNF4 protein (Recombinant) (His-Tag) (STJP017869) E.coli SDS-PAGE
STJP017870 Human NDUFA5 protein (Recombinant) (His-Tag) (STJP017870) E.coli SDS-PAGE

Related Products

!