Name: Human KNTC1 (Kinetochore-associated protein 1) Sandwich ELISA Kit Kit (STJE0010213)
SKU: STJE0010213
Availability: InStock

Human KNTC1 (Kinetochore-associated protein 1) Sandwich ELISA Kit Kit (STJE0010213)

SKU:

STJE0010213

£501.50 - £688.50

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Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.056ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This KNTC1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids..

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	KNTC1
Gene ID:	9735
Uniprot ID:	KNTC1_HUMAN
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	High expression in testis.
Post Translational Modifications
Function	Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Protein Name	Kinetochore-Associated Protein 1 Rough Deal Homolog Hsrod Rod Hrod
Database Links	Reactome: R-HSA-141444 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-68877 Reactome: R-HSA-9648025
Cellular Localisation	Cytoplasm Nucleus Chromosome Centromere Kinetochore Cytoskeleton Spindle Dynamic Pattern Of Localization During The Cell Cycle At Interphase Uniformly Distributed Throughout The Cytoplasm And Nucleus By Prophase And Until Late Stages Of Prometaphase A Fraction Of The Total Pool Is Concentrated At Kinetochores By Metaphase Detected At Kinetochores Along Spindle Fibers And Most Prominently At The Poles By Late Anaphase Until The End Of Telophase No Longer Detectable On Kinetochores Or Along Spindle Fibers But Still Present At The Spindle Poles
Alternative ELISA Names	Kinetochore-Associated Protein 1 ELISA kit Rough Deal Homolog ELISA kit Hsrod ELISA kit Rod ELISA kit Hrod ELISA kit KNTC1 ELISA kit KIAA0166 ELISA kit ROD ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
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Human KNTC1 (Kinetochore-associated protein 1) Sandwich ELISA Kit Kit (STJE0010213)