Human KMO protein (Recombinant) (N-His) (STJP003227)

SKU:
STJP003227
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KMO-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KMO
Gene ID: 8564
Uniprot ID: KMO_HUMAN
Immunogen Region: Met1-Glu366
Immunogen: Homo sapiens (Human)
Function Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
Protein Name Kynurenine 3-Monooxygenase
Kynurenine 3-Hydroxylase
Database Links Reactome: R-HSA-71240
Cellular Localisation Mitochondrion Outer Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Kynurenine 3-Monooxygenase protein
Kynurenine 3-Hydroxylase protein
KMO protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP010558 Pseudomonas fluorescens kmo/PfKMO protein (Recombinant) (N-His) (STJP010558) E. coli
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells

Related Products

!