Human KLKB1 protein (Recombinant) (N-His) (STJP003630)

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STJP003630
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KLKB1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KLKB1
Gene ID: 3818
Uniprot ID: KLKB1_HUMAN
Immunogen Region: Ala65-Phe348
Immunogen: Homo sapiens (Human)
Function Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Protein Name Plasma Kallikrein
Fletcher Factor
Kininogenin
Plasma Prekallikrein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-1592389
Reactome: R-HSA-9657688
Reactome: R-HSA-9657689
Cellular Localisation Secreted
Alternative Protein Names Plasma Kallikrein protein
Fletcher Factor protein
Kininogenin protein
Plasma Prekallikrein protein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain protein
KLKB1 protein
KLK3 protein

Information sourced from Uniprot.org