Human KLF15 (Kruppel Like Factor 15) Sandwich ELISA Kit Kit (STJE0010176)

Human KLF15 (Kruppel Like Factor 15) Sandwich ELISA Kit Kit (STJE0010176)

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STJE0010176
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.068ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This KLF15 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: KLF15
Gene ID: 28999
Uniprot ID: KLF15_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Highly expressed in liver, skeletal muscle, and kidney. Expressed in cardiomyocytes. Expression is highly reduced in cardiac tissue of patients with non-ischemic cardiomyopathy and aortic aneurysm, and in glomerular disease. Not expressed in bone marrow or lymphoid tissues.
Post Translational Modifications
Function Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart. Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4. Involved in podocyte differentiation. Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.
Protein Name Krueppel-Like Factor 15
Kidney-Enriched Krueppel-Like Factor
Database Links Reactome: R-HSA-1368108
Cellular Localisation Nucleus
Alternative ELISA Names Krueppel-Like Factor 15 ELISA kit
Kidney-Enriched Krueppel-Like Factor ELISA kit
KLF15 ELISA kit
KKLF ELISA kit
output

Information sourced from Uniprot.org

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