| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human KLC1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | KLC1 |
| Gene ID: | 3831 |
| Uniprot ID: | KLC1_HUMAN |
| Immunogen Region: | Met1-Val254 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles. |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| Protein Name | Kinesin Light Chain 1Klc 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-9725370Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionGrowth ConeCytoplasmic VesicleCytoplasmCytoskeleton |
| Alternative Protein Names | Kinesin Light Chain 1 proteinKlc 1 proteinKLC1 proteinKLC proteinKNS2 protein |
Information sourced from Uniprot.org