Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human KIR2DL1-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
Conjugation: |
Biotin |
Formulation: |
Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: |
Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: |
The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: |
KIR2DL1 |
Gene ID: |
3802 |
Uniprot ID: |
KI2L1_HUMAN |
Immunogen Region: |
His22-Arg242 |
Immunogen: |
DNA sequence encoding Human KIR2DL1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Function | Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis. |
Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl1Cd158 Antigen-Like Family Member ANatural Killer-Associated Transcript 1Nkat-1P58 Natural Killer Cell Receptor Clones Cl-42/47.11P58 Nk Receptor Cl-42/47.11P58.1 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158a |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 2dl1 proteinCd158 Antigen-Like Family Member A proteinNatural Killer-Associated Transcript 1 proteinNkat-1 proteinP58 Natural Killer Cell Receptor Clones Cl-42/47.11 proteinP58 Nk Receptor Cl-42/47.11 proteinP58.1 Mhc Class-I-Specific Nk Receptor proteinCd Antigen Cd158a proteinKIR2DL1 proteinCD158A proteinNKAT1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance