Name: Human KIF5A protein (Recombinant) (N-His) (STJP005257)
SKU: STJP005257
Availability: InStock

Human KIF5A protein (Recombinant) (N-His) (STJP005257)

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STJP005257

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human KIF5A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
Protein Name	Kinesin Heavy Chain Isoform 5a Kinesin Heavy Chain Neuron-Specific 1 Neuronal Kinesin Heavy Chain Nkhc
Database Links	Reactome: R-HSA-2132295 Reactome: R-HSA-264876 Reactome: R-HSA-5625970 Reactome: R-HSA-6811434 Reactome: R-HSA-983189
Cellular Localisation	Cytoplasm Perinuclear Region Cytoskeleton Perikaryon Concentrated In The Cell Body Of The Neurons Particularly In The Perinuclear Region
Alternative Protein Names	Kinesin Heavy Chain Isoform 5a protein Kinesin Heavy Chain Neuron-Specific 1 protein Neuronal Kinesin Heavy Chain protein Nkhc protein KIF5A protein NKHC1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP007400	Human KIF5A protein (Recombinant) (N-His) (STJP007400)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP002980	Human KLHL20 protein (Recombinant) (N-His) (STJP002980)	HEK293 cells
STJP003027	Human CCL3L1 protein (Recombinant) (N-His) (STJP003027)	HEK293 cells

Human KIF5A protein (Recombinant) (N-His) (STJP005257)

General Information