| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.118ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description : | This KIF5A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | KIF5A |
| Gene ID: | 3798 |
| Uniprot ID: | KIF5A_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Distributed throughout the CNS but is highly enriched in subsets of neurons. |
| Post Translational Modifications | |
| Function | Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
| Protein Name | Kinesin Heavy Chain Isoform 5a Kinesin Heavy Chain Neuron-Specific 1 Neuronal Kinesin Heavy Chain Nkhc |
| Database Links | Reactome: R-HSA-2132295 Reactome: R-HSA-264876 Reactome: R-HSA-5625970 Reactome: R-HSA-6811434 Reactome: R-HSA-983189 |
| Cellular Localisation | Cytoplasm Perinuclear Region Cytoskeleton Perikaryon Concentrated In The Cell Body Of The Neurons Particularly In The Perinuclear Region |
| Alternative ELISA Names | Kinesin Heavy Chain Isoform 5a ELISA kit Kinesin Heavy Chain Neuron-Specific 1 ELISA kit Neuronal Kinesin Heavy Chain ELISA kit Nkhc ELISA kit KIF5A ELISA kit NKHC1 ELISA kit |
| output |
Information sourced from Uniprot.org