Human KIF5A (Kinesin Family, Member 5A) Sandwich ELISA Kit (STJE0010155)
SPECIFICATIONS
General Information
| Short Description | This KIF5A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.118ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | KIF5A |
| Gene ID | 3798 |
| Uniprot ID | KIF5A_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Distributed throughout the CNS but is highly enriched in subsets of neurons. |
| Post Translational Modifications | |
| Function | Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
| Protein Name | Kinesin Heavy Chain Isoform 5aKinesin Heavy Chain Neuron-Specific 1Neuronal Kinesin Heavy ChainNkhc |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-264876Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonPerikaryonConcentrated In The Cell Body Of The NeuronsParticularly In The Perinuclear Region |
| Alternative ELISA Names | Kinesin Heavy Chain Isoform 5a ELISA kitKinesin Heavy Chain Neuron-Specific 1 ELISA kitNeuronal Kinesin Heavy Chain ELISA kitNkhc ELISA kitKIF5A ELISA kitNKHC1 ELISA kit |
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Information sourced from Uniprot.org