| Function | Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation. Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity. Required for asymmetrical localization of CEP120 to daughter centrioles. |
| Protein Name | Protein Talpid3 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomePhotoreceptor Inner SegmentCentrioleCilium Basal BodyForms A Ring-Like Structure At The Extreme Distal End Of Both Mother And Daughter CentriolesIn Photoreceptor Cells Localized To The Joint Between The Inner And Outer SegmentsSpecifically Localized At The Mother Centriole (Basal Body) And The Adjacent Centriole As Well As Between The Two Centrioles But Not In The Connecting Cilium |
| Alternative Protein Names | Protein Talpid3 proteinKIAA0586 proteinTALPID3 protein |
Information sourced from Uniprot.org
