Human KCNJ6 protein (Recombinant) (N-His) (STJP015759)

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STJP015759
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Short Description :Recombinant-Human KCNJ6-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:KCNJ6
Gene ID:3763
Uniprot ID:KCNJ6_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gln195-Pro380
Function Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors.
Protein Name G Protein-Activated Inward Rectifier Potassium Channel 2
Girk-2
Bir1
Inward Rectifier K(+ Channel Kir3.2
Katp-2
Potassium Channel - Inwardly Rectifying Subfamily J Member 6
Database Links Reactome: R-HSA-1296041
Reactome: R-HSA-997272
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Protein Names G Protein-Activated Inward Rectifier Potassium Channel 2 protein
Girk-2 protein
Bir1 protein
Inward Rectifier K(+ Channel Kir3.2 protein
Katp-2 protein
Potassium Channel - Inwardly Rectifying Subfamily J Member 6 protein
KCNJ6 protein
GIRK2 protein
KATP2 protein
KCNJ7 protein

Information sourced from Uniprot.org

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