| Tissue Specificity | Detected in muscle, brain, lung, heart and kidney. |
| Post Translational Modifications | |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. |
| Protein Name | Solute Carrier Family 12 Member 7Electroneutral Potassium-Chloride Cotransporter 4K-Cl Cotransporter 4 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Solute Carrier Family 12 Member 7 ELISA kitElectroneutral Potassium-Chloride Cotransporter 4 ELISA kitK-Cl Cotransporter 4 ELISA kitSLC12A7 ELISA kitKCC4 ELISA kit |
| output | |
Information sourced from Uniprot.org