Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Kit (STJE0010119)

Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Kit (STJE0010119)

SKU:
STJE0010119
£446.50 - £611.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.133ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This JAM1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: F11R
Gene ID: 50848
Uniprot ID: JAM1_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in endothelium, epithelium and leukocytes (at protein level).
Post Translational Modifications N-glycosylated. (Microbial infection) Cleaved by H.pylori virulence factor PqqE. Cleavage leads to altered tight junction functions.
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1. (Microbial infection) Acts as a receptor for Human Rotavirus strain Wa.
Protein Name Junctional Adhesion Molecule A
Jam-A
Junctional Adhesion Molecule 1
Jam-1
Platelet F11 Receptor
Platelet Adhesion Molecule 1
Pam-1
Cd Antigen Cd321
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-216083
Reactome: R-HSA-2173791
Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Single-Pass Type I Membrane Protein
Localized At Tight Junctions Of Both Epithelial And Endothelial Cells
Alternative ELISA Names Junctional Adhesion Molecule A ELISA kit
Jam-A ELISA kit
Junctional Adhesion Molecule 1 ELISA kit
Jam-1 ELISA kit
Platelet F11 Receptor ELISA kit
Platelet Adhesion Molecule 1 ELISA kit
Pam-1 ELISA kit
Cd Antigen Cd321 ELISA kit
F11R ELISA kit
JAM1 ELISA kit
JCAM ELISA kit
UNQ264 ELISA kit
PRO301 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0016505 Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016505) Human ELISA
STJE0010120 Human JAM2 (Junctional Adhesion Molecule 2) Sandwich ELISA Kit Kit (STJE0010120) Human ELISA
STJE0010121 Human JAM3 (Junctional Adhesion Molecule 3) Sandwich ELISA Kit Kit (STJE0010121) Human ELISA
STJE0016507 Human JAM3 (Junctional Adhesion Molecule 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016507) Human ELISA
STJE0016506 Human JAM2 (Junctional Adhesion Molecule 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016506) Human ELISA
!