Human ITIH2 protein (Recombinant) (N-His) (STJP004256)

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STJP004256
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ITIH2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ITIH2
Gene ID: 3698
Uniprot ID: ITIH2_HUMAN
Immunogen Region: Gly452-Asp702
Immunogen: Homo sapiens (Human)
Post Translational Modifications Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. Phosphorylated by FAM20C in the extracellular medium.
Function May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Protein Name Inter-Alpha-Trypsin Inhibitor Heavy Chain H2
Iti Heavy Chain H2
Iti-Hc2
Inter-Alpha-Inhibitor Heavy Chain 2
Inter-Alpha-Trypsin Inhibitor Complex Component Ii
Serum-Derived Hyaluronan-Associated Protein
Shap
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Inter-Alpha-Trypsin Inhibitor Heavy Chain H2 protein
Iti Heavy Chain H2 protein
Iti-Hc2 protein
Inter-Alpha-Inhibitor Heavy Chain 2 protein
Inter-Alpha-Trypsin Inhibitor Complex Component Ii protein
Serum-Derived Hyaluronan-Associated Protein protein
Shap protein
ITIH2 protein
IGHEP2 protein

Information sourced from Uniprot.org

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