Human ITIH2 protein (Recombinant) (N-His) (STJP004256)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP004256
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General Information

Short DescriptionRecombinant-Human ITIH2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolITIH2
Gene ID3698
Uniprot IDITIH2_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGly452-Asp702

Additional Info

Post Translational Modifications Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. Phosphorylated by FAM20C in the extracellular medium.
Function May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Protein Name Inter-Alpha-Trypsin Inhibitor Heavy Chain H2
Iti Heavy Chain H2
Iti-Hc2
Inter-Alpha-Inhibitor Heavy Chain 2
Inter-Alpha-Trypsin Inhibitor Complex Component Ii
Serum-Derived Hyaluronan-Associated Protein
Shap
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Inter-Alpha-Trypsin Inhibitor Heavy Chain H2 protein
Iti Heavy Chain H2 protein
Iti-Hc2 protein
Inter-Alpha-Inhibitor Heavy Chain 2 protein
Inter-Alpha-Trypsin Inhibitor Complex Component Ii protein
Serum-Derived Hyaluronan-Associated Protein protein
Shap protein
ITIH2 protein
IGHEP2 protein

Information sourced from Uniprot.org

Citations

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