Name: Human ITGB8 protein (Recombinant) (N-His) (STJP004432)
SKU: STJP004432
Availability: InStock

Human ITGB8 protein (Recombinant) (N-His) (STJP004432)

SKU:

STJP004432

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ITGB8-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (Probable). Required during vasculogenesis.
Protein Name	Integrin Beta-8
Database Links	Reactome: R-HSA-2129379 Reactome: R-HSA-216083 Reactome: R-HSA-2173789
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Integrin Beta-8 protein ITGB8 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP011109	Mouse ITGB8 protein (Recombinant) (N-His) (STJP011109)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP006145	Human TJP2 protein (Recombinant) (N-His) (STJP006145)	E. coli
STJP009675	Human NEIL3 protein (Recombinant) (N-His) (STJP009675)	E. coli

Human ITGB8 protein (Recombinant) (N-His) (STJP004432)

General Information