Human IRF6 protein (Recombinant) (N-His) (STJP003207)

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STJP003207
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IRF6-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IRF6
Gene ID: 3664
Uniprot ID: IRF6_HUMAN
Immunogen Region: Glu196-Thr445
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation.
Function Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development. Plays a role in regulating mammary epithelial cell proliferation. May regulate WDR65 transcription.
Protein Name Interferon Regulatory Factor 6
Irf-6
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-909733
Cellular Localisation Nucleus
Cytoplasm
Translocates To Nucleus In Response To An Activating Signal
Alternative Protein Names Interferon Regulatory Factor 6 protein
Irf-6 protein
IRF6 protein

Information sourced from Uniprot.org

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