| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.066ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This IRF2BP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | IRF2BP2 |
| Gene ID: | 359948 |
| Uniprot ID: | I2BP2_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-360 is required for nuclear targeting. |
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 2Irf-2-Binding Protein 2Irf-2bp2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative ELISA Names | Interferon Regulatory Factor 2-Binding Protein 2 ELISA kitIrf-2-Binding Protein 2 ELISA kitIrf-2bp2 ELISA kitIRF2BP2 ELISA kit |
| output |
Information sourced from Uniprot.org