Human INTS13 protein (Recombinant) (N-His) (STJP008890)

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STJP008890
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human INTS13-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: INTS13
Gene ID: 55726
Uniprot ID: INT13_HUMAN
Immunogen Region: Ser50-His254
Immunogen: Homo sapiens (Human)
Function Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Protein Name Integrator Complex Subunit 13
Cell Cycle Regulator Mat89bb Homolog
Germ Cell Tumor 1
Protein Asunder Homolog
Sarcoma Antigen Ny-Sar-95
Database Links Reactome: R-HSA-6807505
Cellular Localisation Nucleus
Cytoplasm
Nuclear Location Is Required For Recruitment Of Dynein Motors To Nuclear Envelope At G2/M
Alternative Protein Names Integrator Complex Subunit 13 protein
Cell Cycle Regulator Mat89bb Homolog protein
Germ Cell Tumor 1 protein
Protein Asunder Homolog protein
Sarcoma Antigen Ny-Sar-95 protein
INTS13 protein
ASUN protein
C12orf11 protein
GCT1 protein

Information sourced from Uniprot.org