Function | Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. |
Protein Name | Integrator Complex Subunit 13Cell Cycle Regulator Mat89bb HomologGerm Cell Tumor 1Protein Asunder HomologSarcoma Antigen Ny-Sar-95 |
Database Links | Reactome: R-HSA-6807505 |
Cellular Localisation | NucleusCytoplasmNuclear Location Is Required For Recruitment Of Dynein Motors To Nuclear Envelope At G2/M |
Alternative Protein Names | Integrator Complex Subunit 13 proteinCell Cycle Regulator Mat89bb Homolog proteinGerm Cell Tumor 1 proteinProtein Asunder Homolog proteinSarcoma Antigen Ny-Sar-95 proteinINTS13 proteinASUN proteinC12orf11 proteinGCT1 protein |
Information sourced from Uniprot.org