Human IL34 protein (Recombinant) (C-His) (STJP005611)

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STJP005611
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IL34-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IL34
Gene ID: 146433
Uniprot ID: IL34_HUMAN
Immunogen Region: Asn21-Pro242
Immunogen: Homo sapiens (Human)
Function Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Protein Name Interleukin-34
Il-34
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9680350
Cellular Localisation Secreted
Alternative Protein Names Interleukin-34 protein
Il-34 protein
IL34 protein
C16orf77 protein

Information sourced from Uniprot.org