Human IL31RA protein (Recombinant) (N-His) (STJP005734)

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STJP005734
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IL31RA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IL31RA
Gene ID: 133396
Uniprot ID: IL31R_HUMAN
Immunogen Region: Val130-Asp622
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.
Protein Name Interleukin-31 Receptor Subunit Alpha
Il-31 Receptor Subunit Alpha
Il-31r Subunit Alpha
Il-31r-Alpha
Il-31ra
Cytokine Receptor-Like 3
Glm-R
Hglm-R
Gp130-Like Monocyte Receptor
Gp130-Like Receptor
Zcytor17
Database Links Reactome: R-HSA-6788467
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Presynaptic Cell Membrane
Cell Projection
Axon
Alternative Protein Names Interleukin-31 Receptor Subunit Alpha protein
Il-31 Receptor Subunit Alpha protein
Il-31r Subunit Alpha protein
Il-31r-Alpha protein
Il-31ra protein
Cytokine Receptor-Like 3 protein
Glm-R protein
Hglm-R protein
Gp130-Like Monocyte Receptor protein
Gp130-Like Receptor protein
Zcytor17 protein
IL31RA protein
CRL3 protein
GPL protein
UNQ6368 protein
PRO21073 protein
PRO21384 protein

Information sourced from Uniprot.org