Human IL23R protein (Recombinant-Active) (C-hFc) (STJP012140)

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STJP012140-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human IL23R-C-hFc protein was developed from mammalian cells and has a target region of C-hFc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL23R
Gene ID: 149233
Uniprot ID: IL23R_HUMAN
Immunogen Region: Gly24-Gly355
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated in response to IL23.
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Protein Name Interleukin-23 Receptor
Il-23 Receptor
Il-23r
Database Links Reactome: R-HSA-6785807
Reactome: R-HSA-9020933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-23 Receptor protein
Il-23 Receptor protein
Il-23r protein
IL23R protein

Information sourced from Uniprot.org

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