Human IL18BP protein (Recombinant) (N-His) (STJP003458)

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STJP003458
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IL18BP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IL18BP
Gene ID: 10068
Uniprot ID: I18BP_HUMAN
Immunogen Region: Thr31-Gly194
Immunogen: Homo sapiens (Human)
Post Translational Modifications N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4.
Function Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Protein Name Interleukin-18-Binding Protein
Il-18bp
Tadekinig-Alfa
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Secreted
Alternative Protein Names Interleukin-18-Binding Protein protein
Il-18bp protein
Tadekinig-Alfa protein
IL18BP protein

Information sourced from Uniprot.org

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