| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human IL17RE-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | IL17RE |
| Gene ID: | 132014 |
| Uniprot ID: | I17RE_HUMAN |
| Immunogen Region: | Thr155-His454 |
| Immunogen: | Homo sapiens (Human) |
| Function | Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. |
| Protein Name | Interleukin-17 Receptor EIl-17 Receptor EIl-17re |
| Database Links | Reactome: R-HSA-448424 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: CytoplasmIsoform 3: SecretedIsoform 4: CytoplasmIsoform 5: Secreted |
| Alternative Protein Names | Interleukin-17 Receptor E proteinIl-17 Receptor E proteinIl-17re proteinIL17RE proteinUNQ3056 proteinPRO9877 protein |
Information sourced from Uniprot.org