| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IL-32-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | IL32 |
| Gene ID: | 9235 |
| Uniprot ID: | IL32_HUMAN |
| Immunogen Region: | ECD |
| Immunogen: | DNA sequence encoding the extracellular domain of Human IL32 including a C-terminal His tag was expressed in HEK293 Cells. NA |
| Immunogen Sequence: | MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE KERDGLRCRG NA |
| Tissue Specificity | Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells. |
| Function | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. |
| Protein Name | Interleukin-32Il-32Natural Killer Cells Protein 4Tumor Necrosis Factor Alpha-Inducing Factor |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9013423 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interleukin-32 proteinIl-32 proteinNatural Killer Cells Protein 4 proteinTumor Necrosis Factor Alpha-Inducing Factor proteinIL32 proteinNK4 proteinTAIF protein |
Information sourced from Uniprot.org