| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IL-2RB (CD122)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | Measured by its ability to bind biotinylated recombinant rat IL2 in a functional ELISA. NA |
| Gene Symbol: | IL2RB |
| Gene ID: | 3560 |
| Uniprot ID: | IL2RB_HUMAN |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of human Interleukin-2 receptor beta subunit including an Fc tag was expressed in HEK293 cells. NA |
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaInterleukin-15 Receptor Subunit BetaP70-75P75Cd Antigen Cd122 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8983432Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-2 Receptor Subunit Beta proteinIl-2 Receptor Subunit Beta proteinIl-2r Subunit Beta proteinIl-2rb proteinHigh Affinity Il-2 Receptor Subunit Beta proteinInterleukin-15 Receptor Subunit Beta proteinP70-75 proteinP75 proteinCd Antigen Cd122 proteinIL2RB proteinIL15RB protein |
Information sourced from Uniprot.org
