Human IL-1RA (IL-1RA) Antibody Pair (STJAP00721)
General Information
| Short Description | This IL-1RA antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R02-6W5/R05-7M2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IL1RN |
| Gene ID | 3557 |
| Uniprot ID | IL1RA_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Pair Names | Interleukin-1 Receptor Antagonist Protein antibody pairIl-1rn antibody pairIl-1ra antibody pairIrap antibody pairIcil-1ra antibody pairIl1 Inhibitor antibody pairAnakinra antibody pairIL1RN antibody pairIL1F3 antibody pairIL1RA antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human IL-1RA (IL-1RA) Antibody Pair (STJAP00721)
This antibody pair detects human IL-1RA (Interleukin-1 receptor antagonist), corresponding to UniProt accession P18510. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit-derived monoclonal IgGs. The clone IDs are R02-6W5 and R05-7M2, and both were raised against a recombinant protein immunogen.
Both antibodies are supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2, and purified by affinity chromatography.
This pair is validated for use in ELISA. The working dilution for each antibody should be determined by the end user through titration.
The antibodies should be stored at 4°C for short-term use. For long-term storage, they should be aliquoted and kept at -20°C. Repeated freeze/thaw cycles should be avoided.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.