| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human IL-13 alpha 1 receptor (IL13RA1)-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised 0.2 Mu m filtered 50mM NaCl, 50mM NaAc pH 6.5, and 5% trehalose. |
| Dilution Range: |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. It is recommended to add 0.1% HSA or BSA for long term storage. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
Immobilized recombinant IL13RA1 activity measured by its ability to bind recombinant human Interleukin-13 at a concentration range of 0.1-10 ng/ml. NA |
| Gene Symbol: |
IL13RA1 |
| Gene ID: |
3597 |
| Uniprot ID: |
I13R1_HUMAN |
| Immunogen Region: |
ECD |
| Immunogen: |
Optimized DNA sequence encoding extracellular domain of human IL-13 receptor alpha 1 including a His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary.lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1Il-13 Receptor Subunit Alpha-1Il-13r Subunit Alpha-1Il-13r-Alpha-1Il-13ra1Cancer/Testis Antigen 19Ct19Cd Antigen Cd213a1 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-1 proteinIl-13 Receptor Subunit Alpha-1 proteinIl-13r Subunit Alpha-1 proteinIl-13r-Alpha-1 proteinIl-13ra1 proteinCancer/Testis Antigen 19 proteinCt19 proteinCd Antigen Cd213a1 proteinIL13RA1 proteinIL13R proteinIL13RA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
