| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human IGFBP-8/CTGF-No tag protein was developed from hek293 cells and has a target region of No tag. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCN2 |
| Gene ID: |
1490 |
| Uniprot ID: |
CCN2_HUMAN |
| Immunogen Region: |
Gln27-Ala180 |
| Immunogen: |
Recombinant Human IGFBP-8/CTGF Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Gln27-Ala180) of human CTGF (Accession #P29279) fused with no tags. |
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Ccn Family Member 2 proteinCellular Communication Network Factor 2 proteinConnective Tissue Growth Factor proteinHypertrophic Chondrocyte-Specific Protein 24 proteinInsulin-Like Growth Factor-Binding Protein 8 proteinIbp-8 proteinIgf-Binding Protein 8 proteinIgfbp-8 proteinCCN2 proteinCTGF proteinHCS24 proteinIGFBP8 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
